Endothelial Cells form thin protective lining inside the blood vessels. It has a significant role in maintaining tissue homeostasis and maintaining adequate circulation. These cells help regulate blood flow, control the movement of nutrients and oxygen, and support communication between the bloodstream and surrounding tissues. These cells manage inflammation, blood clotting, and blood pressure. When endothelial cells function properly, they help keep blood vessels flexible and healthy. Damage to these cells can contribute to conditions such as heart disease, diabetes, and vascular disorders. Because of their importance, endothelial cells are widely studied in cardiovascular research and regenerative medicine. Kosheeka, India isolated and supplies various primary and secondary cells for research purposes.